The entertainer wouldn’t elaborate on his conspiracy belief, citing the court-imposed gag order that prevents him from discussing his trial in detail.
However, he said he believes he is just the latest of several “black luminaries” to be unjustly accused.
He said he was drawing inspiration from the cases of former South African President Nelson Mandela and former heavyweight boxing champions Muhammad Ali and Jack Johnson.
“I just want to say to fans in every corner of the Earth, every nationality, every race, every language, I love you from the bottom of my heart,” Jackson said.
“I would love your prayers and your goodwill, and please be patient and be with me and believe in me because I am completely, completely innocent. But please know a lot of conspiracy is going on as we speak.”
Jackson also claimed he is in “intense pain” since falling in the shower earlier this month, although he said at another point that his health was perfect.
Earlier this month he arrived late to court wearing pyjama bottoms, a T-shirt and walking stiffly, his representatives said at the time he had been treated at a hospital for a serious back injury.
“I was coming out of the shower and I fell and all my body weight. I’m pretty fragile. All my body weight fell against my rib cage,” Jackson said. “And I bruised my lung very badly.”
He said the injury has caused him to cough up blood and was so painful that it brought him to tears in court one day when he was seen wiping his eyes with a tissue. He said he remains under a doctor’s care.
The entertainer also denied recent rumours he’s teetering on the verge of bankruptcy.
“That’s not true at all. It’s just one of their many schemes to embarrass me. It’s to drag me through the mud,” he said.
Reverend Jackson told The Associated Press earlier this month he and Jackson frequently pray together, and he told his audience Sunday he speaks by phone with the entertainer nearly every day.
Jackson, a Jehovah’s Witness, said prayer is helping him get through his trial, which resumes Monday.
“I gain strength from God. I believe in Jehovah God very much,” he said.
Asked the lowest point in his life, he responded: “Probably the low point, the lowest point emotionally, is probably what I’m going through.”
Jackson made his comments on the eve to what’s expected to be a pivotal day in his trial.
On Monday Judge Rodney Melville will hear arguments from rival lawyers to help him decide whether jurors should be given details of earlier child sex accusations against Jackson.
The prosecution hopes testimony from at least two previous cases would help demonstrate a pattern of child molestation in the superstar’s past.
The civil cases have never been publicly heard as they were settled out of court, but Jackson is known to have paid US$20m (A$26m) to a boy who claims the star molested him at age 13 in 1993, and another US$2m to the son of a former employee.
Melville has given the prosecution and the defence three hours to make their cases before the jury is allowed in for the continuation of the trial.